Yes! LIVKRFT now offers fully compliant NAD+ on same day basis due to a reclassification by the FDA. The Best NAD+ La Jolla is now available for office use through one of our amazing pharmacy partners. This means LIVKRAFT can now keep La Jolla NAD+ IV onsite and available when you want and need it. We are absolutely thrilled that the FDA has reclassified NAD+ La Jolla.

Deciding on the appropriate dosage of NAD+ for IV therapy—or any other mode of administration—depends on various factors, including your individual health status, the objectives for the treatment, and potential side effects.

Our incredible team of Longevity Medical Professionals will discuss your goals, lifestyle, and medical history to create a customized solution tailored to YOU.

Here are some factors that our team will be considering when coming to a dosage recommendation.

1. Purpose of Treatment:

   - Therapeutic Use: If you're using NAD+ IV therapy for specific conditions like addiction recovery, chronic fatigue, or neurodegenerative conditions, the required dose might be different than for general wellness or anti-aging.

   - Wellness and Anti-Aging: For general wellness, a lower dose might be appropriate compared to therapeutic applications.

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2. Tolerance:

   - Some people might experience side effects at higher doses, such as flushing, chest tightness, or nausea. It's essential to start at a dose that's comfortable for you and adjust as needed.

   - Some clinics or providers might start you on a lower dose to assess your tolerance and then adjust the dose in subsequent sessions.

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3. Frequency:

   - Depending on how often you plan to undergo NAD+ IV therapy, the dosage might vary. For instance, a more frequent treatment schedule might call for a lower individual dose.

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4. Body Size and Composition:

   - In some cases, dosages might be adjusted based on body weight or body mass index (BMI). Larger individuals might require a higher dose, but this isn't a strict rule and other factors play into dosage decisions..

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NAD+ IV therapy offers potential benefits, but like any medical procedure or treatment, it's not suitable for everyone. There are certain individuals and circumstances where caution is advised or where NAD+ IV might be contraindicated:

1. Pregnancy and Breastfeeding: There's limited data on the effects of NAD+ IV therapy during pregnancy and breastfeeding. Until more information is available, it's best to err on the side of caution and avoid the treatment during these periods.

2. Heart Conditions: People with certain heart conditions, especially those related to heart failure or unstable angina, should approach NAD+ IV with caution. Rapid administration of the IV can sometimes lead to increased blood pressure or chest tightness.

3. Kidney Disorders: Those with kidney disorders or compromised kidney function should consult with their nephrologist before undergoing any IV therapy, including NAD+.

4. Current Medications: Some medications might interact with NAD+ or the other components in the IV solution. It's crucial to disclose all current medications to the provider before undergoing treatment.

5. Allergies: While rare, some people might be allergic to components of the IV solution.

6. History of Seizures: There's a potential (though rare) risk of seizures associated with high doses of NAD+. If you have a history of seizures, it's essential to discuss this with your healthcare provider.

7. Recent Surgeries or Medical Procedures: If you've recently had surgery or any significant medical procedure, it's a good idea to consult with your primary care physician or surgeon before undergoing NAD+ IV therapy.

8. Uncontrolled Chronic Conditions: Conditions like uncontrolled diabetes could put you at higher risk of complications from any IV therapy. It's important to manage such conditions and consult with a specialist before undergoing NAD+ treatments.

9. Children and Adolescents: The safety and efficacy of NAD+ IV therapy in younger populations have not been well-studied. It's generally advised to avoid such treatments in children and adolescents unless there's a specific medical indication.

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I Remember, while NAD+ IV therapy has potential benefits, it's crucial to approach it (and any medical treatment) with a comprehensive understanding of the risks and benefits after consulting with a LIVKRAFT medical professional or your primary care physician or other specialist.

NAD+ (Nicotinamide Adenine Dinucleotide) levels are known to decrease with age in various organisms, including humans. However, quantifying the exact decrease can be somewhat challenging due to variations among individuals and differences in study methodologies. 

Several studies have demonstrated this decline:

1. Mouse Studies: In mouse models, a significant decline in NAD+ levels has been observed in multiple tissues, including the skin, brain, and muscles, as the mice age. For example, some studies have shown that by old age, NAD+ concentrations in certain tissues can drop to half or even less than those found in young mice.

2. Human Studies: Directly measuring NAD+ in humans across a wide age range is more limited than in model organisms. However, some studies have indicated a decline in various human tissues. For instance, a study on human skin found a decrease in NAD+ levels correlating with age. 

3. Mechanisms of Decrease: The decrease in NAD+ levels with age might be due to multiple factors:

    - Increased Consumption: As DNA damage accumulates with age, the body uses more NAD+ to facilitate DNA repair processes, consuming the available stores.

    - Decreased Production: There may also be a reduction in the body's ability to synthesize and recycle NAD+ as we age.

    - Enzymatic Breakdown: Enzymes like CD38, which break down NAD+, increase with age, further depleting available NAD+ levels.

4. Consequences of Decrease: The reduction in NAD+ levels with age has been associated with various age-related conditions, including metabolic disorders, neurodegenerative diseases, and reduced mitochondrial function.

Given the potential importance of NAD+ in aging and age-related diseases, there's substantial interest in therapeutic strategies to boost NAD+ levels in older individuals. This includes supplementation with NAD+ precursors like nicotinamide riboside (NR) or nicotinamide mononucleotide (NMN).

In summary, while it's clear that NAD+ levels generally decrease with age, the exact percentage of reduction can vary based on the tissue, individual factors, and the methods of measurement. It's a topic of ongoing research, and we're still uncovering the full implications of this decline in the context of human health and aging.

The frequency of NAD+ IV therapy depends on several factors, including your health objectives, the specific medical or wellness conditions you're addressing, and recommendations from your healthcare provider. Here are some general guidelines:

1. Therapeutic Use: For individuals using NAD+ IV therapy to address specific medical conditions, such as addiction recovery, depression, or chronic fatigue syndrome, the initial treatments might be more frequent. For instance, during detox or addiction recovery, patients might receive NAD+ IV therapy daily for a period of 10 days to 2 weeks.

2. Anti-Aging and Wellness: Those seeking NAD+ IV therapy for its potential anti-aging benefits or to combat the general effects of aging might opt for regular sessions spaced out more broadly. This could mean once a month, every few months, or even semi-annually, depending on individual needs and the recommendations of the provider.

3. Athletic Recovery: Athletes or individuals using NAD+ for its potential benefits in muscle recovery and energy boost might choose to have treatments post-competition or after intense training sessions.

4. Maintenance: After an initial series of treatments to address specific concerns, some people transition into a maintenance phase, where they might receive NAD+ IV therapy less frequently to maintain its benefits.

5. Personalized Approach: The optimal frequency can vary widely among individuals. It's important to consult with a healthcare provider or specialist in NAD+ therapy to tailor the treatment to your specific needs and health goals.

6. Safety Considerations: While NAD+ IV therapy is generally well-tolerated, there are potential side effects, such as flushing, shortness of breath, chest tightness, or nausea. It's essential to work closely with a medical professional who can monitor these effects and adjust treatment frequency or dosage accordingly.

Lastly, while there's significant anecdotal evidence and some preliminary research supporting the benefits of NAD+ IV therapy, it's worth noting that more extensive, controlled studies are still needed to fully understand the therapy's benefits, optimal dosing, and long-term effects. Always make health decisions based on comprehensive information and professional guidance.

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NAD+ (Nicotinamide Adenine Dinucleotide) is a coenzyme present in all living cells and is vital for numerous biological processes. Here's a brief overview of the amazing and powerful NAD+:

1. Cellular Metabolism: NAD+ plays a critical role in cellular metabolism. It's a cofactor for various enzymes, helping them convert nutrients into energy. In particular, it's crucial in the processes of glycolysis, the citric acid cycle, and oxidative phosphorylation, all of which produce ATP, the cell's primary energy currency.

2. Redox Reactions: NAD+ is involved in redox (reduction-oxidation) reactions in the cell. It exists in two forms: the oxidized form (NAD+) and the reduced form (NADH). The ability to shuttle electrons between these forms makes it integral to the body's energy production processes.

3. DNA Repair: One of the most promising areas of NAD+ research relates to its role in DNA repair. NAD+ is required by the PARP (Poly [ADP-ribose] polymerase) proteins, which help repair damaged DNA.

4. Sirtuins Activation: Sirtuins are proteins that regulate various cellular processes, including DNA repair, cell survival, and inflammation. They require NAD+ to function. Sirtuins have been associated with extending lifespan in many organisms, which has sparked interest in NAD+ in the context of aging and longevity.

5. Calcium Signaling: NAD+ plays a role in calcium signaling, a critical process for cell communication, muscle contraction, and other cellular activities.

6. Neuroprotection: There is evidence that NAD+ may have neuroprotective effects, which could have implications for neurodegenerative diseases like Alzheimer's and Parkinson's.

7. Aging and Longevity: As organisms age, NAD+ levels tend to decrease, leading researchers to speculate that replenishing NAD+ might combat some age-related diseases or even influence the aging process.

Given its critical role in so many biological processes and potential implications in age-related diseases, there's significant interest in NAD+ among researchers, clinicians, and the wellness industry.

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When our clients feel the initial signs of a cold or flu coming on, they immediately book an IV therapy session. Our IVs feature a carefully crafted blend of nutrients that collaboratively support health and speed up recovery. 

Vitamin C plays a central role in enhancing the immune system's response. This potent antioxidant supports white blood cells in their battle against invaders, aiding in reducing the severity and duration of illness. 

B-12 is a powerhouse for both energy and immune health. It assists in the formation of red blood cells, which transport oxygen and nutrients throughout the body, while also helping immune cells function at their best.

Zinc plays a vital part in immune defense by regulating immune cell activity and promoting the production of antibodies. It's essential for maintaining the integrity of the skin and mucous membranes, acting as a barrier against pathogens.

The Lactated Ringer solution ensures optimal hydration, aiding the body's natural detoxification processes and maintaining the balance of electrolytes crucial for overall wellness.

Glutathione acts as a potent antioxidant and detoxifier, supporting the body's ability to neutralize harmful substances and reduce oxidative stress.

Lysine is an amino acid that contributes to immune system modulation, supporting the body's ability to fight off infections.

The PlenishIV complex, comprising B-complex vitamins, magnesium, and calcium, contributes to overall wellness by providing essential nutrients for cellular function, energy production, and maintaining bone health.

As the IV solution efficiently navigates the bloodstream, these components are delivered directly to where they're needed most. Additionally, if symptoms are currently making a scene, we offer Zofran, an established anti-nausea solution, and Toradol, a proven non-steroidal anti-inflammatory drug. These additions aim to provide comfort and create an ideal environment for the body's natural healing process.

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IV Therapy excels in delivering nutrients and boosting efficacy, setting it apart from methods like taking vitamins orally or via intramuscular injection. Through direct infusion into your bloodstream, essential nutrients like Vitamin C and B-12 are efficiently absorbed, potentially yielding faster and more noticeable results. This personalized approach stands out by offering maximum nutrient availability and tailored support for your well-being.

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Absorption is key when discussing the efficacy of nutrient delivery. When you take vitamins orally, studies have shown that only about 20-50% of the ingredients are absorbed into the bloodstream. This absorption rate can vary based on several factors including the health of one's digestive system, the presence of other foods or medications, and more. On the other hand, IV Therapy ensures a direct delivery to the bloodstream with an absorption rate of nearly 100%. This means that the body gets to utilize every bit of the nutrients infused, ensuring maximum benefit. For those wanting certainty in the efficacy of their nutrient intake, IV Therapy offers a more direct and guaranteed approach.

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The frequency of IV therapy sessions is tailored to your unique needs, goals, health conditions, and lifestyle. Our healthiest clients, who come in every day telling us how incredible they feel, experience the most success with weekly vitamin IV therapy and bi-monthly NAD+ infusions. We also have clients who are so committed to achieving the best version of themselves that they opt for weekly NAD+ and vitamin IV therapy.

A number of clients are experiencing a specific or chronic health issue that requires them to come in daily, or every other day, for various infusions on the advice of their personal physician or one of the esteemed LIVKRAFT Longevity Medical Physicans after doing comprehensive bloodwork.  

Then there are the elite athletes, who come in daily for IV Therapy to ensure they are experiencing the fastest possible recovery time to be the best at whatever activity or sport that they love. 

These proactive, dedicated, happy, and healthy clients also opt for IV Therapy when they sense a cold or illness approaching, as part of pre-and post-travel wellness protocol, or if they have had a little bit too much fun the night before.